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In addition to its enhanced structural stability, JSKN003 retains the superior HER2-binding and internalization properties of KN026, ensuring efficient payload delivery to trastuzumab-resistant tumor cells

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The main comparators include Wegovy (semaglutide) , Saxenda (liraglutide) , and Orlistat

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Differential gene expression studies in treated animals reveal changes in synaptic function and receptor trafficking genes in key brainstem regions after chronic administration

Adv Mater 35:e2209690 Pan W, Cheng J, Cao X, Zheng Y, Yang Z, Feng W, Chen Y, Wu R (2024) Niobium carbide MXenzyme-driven comprehensive cholesterol regulation for photoacoustic image-guided and anti-inflammatory photothermal ablation in atherosclerosis